Saturday, April 27, 2013

Pick-by-pick draft analysis? |? Draft?chatter

CollegeBasketballTalk

College hoops news and rumors
? CBT on NBCSports.com

Off the Bench

An irreverent, offbeat look at sports
? OTB on NBCSports.com

Source: http://www.rotoworld.com/playernews/nfl/football-player-news/

mac virus santorum drops out bby zimmerman website miami marlins marlins marlins

Six ways to get the most from your credit card

American Express offers a Blue Cash Preferred card that offers 6 percent cash back on groceries, 3 percent on gas, and 1 percent on all other purchases. If you buy $1,300 worth of groceries in a year, the annual rewards will pay for the $75 annual fee. (Mike Blake/Reuters/File)

Cash-back rewards programs?offer you a rebate in the form of a check or statement credit when you purchase with your credit card. The American Express Blue Cash Preferred card, for example, offers 6 percent cash back on groceries, 3 percent on gas, and 1 percent on all other purchases. The card comes with a $75 annual fee, so you should weigh that charge against what you expect to earn in rebates before you apply.

Use your card responsibly and pay your bill in full every month to ensure you're getting the better end of the bargain. Rewards can be a wonderful incentive to sign up for a credit card, just make sure you manage yours effectively.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/47c9IbYfpuY/Six-ways-to-get-the-most-from-your-credit-card

kansas ohio state wrestlemania results womens final four josh hutcherson google april fools office space shell houston open

UK shale gas bonanza 'not assured'

Shale gas in the UK could help secure domestic energy supplies but may not bring down prices, MPs report.

The US boom in shale gas has brought energy prices tumbling and revitalised heavy industry, but the Energy and Climate Change Committee warns conditions are different in Britain.

The MPs say the UK's shale gas developers will face technological uncertainties with different geology.

And public opinion may also be more sceptical, they add.

The UK is a more densely populated landscape, and shale gas operations will be closer to settlements as a consequence.

'Cash sweeteners'

The MPs believe operators will have to overcome potentially tighter regulations.

What is more, the extent of recoverable resources in the UK is also unknown, so the report concludes that it is too soon to say whether shale gas will achieve US-style levels of success.

Continue reading the main story

?Start Quote

Fracking is dirty and unnecessary - it's little wonder so many communities are in opposition?

End Quote Tony Bosworth Friends of the Earth

The MPs argue that this means the Treasury cannot afford to base the UK?s energy strategy on the expectation of cheap British shale gas.

They urge the government to stop "dithering" over energy policy, though, and to ensure there is a system to rebut what "scare stories" may arise over the environmental impacts of shale gas.

And they applaud the government's decision to offer cash sweeteners to people near shale gas facilities.

Success with shale gas will reduce dependence on imports and increase tax revenues, they say, but there is a downside: if it takes off, shale gas will shatter the UK's statutory climate change targets unless the government moves much faster with carbon capture and storage technology.

Tim Yeo, chairman of the Energy and Climate Change Committee, said: "It is still too soon to call whether shale gas will provide the silver bullet needed to solve our energy problems.

"Although the US shale gas has seen a dramatic fall in domestic gas prices, a similar 'revolution' here is not certain."

Tony Bosworth, from Friends of the Earth, responded: "This does little to back the case for a UK shale gas revolution.

"Fracking is dirty and unnecessary ? it's little wonder so many communities are in opposition. We should be building an affordable power system based on our abundant clean energy from the wind, waves and sun.?

'Front and centre'

And Jenny Banks from WWF-UK said: "It's simply impossible to keep global warming below 2C and burn all known fossil fuel reserves ? let alone exploit unconventional reserves like shale gas.

"In other words, the climate impacts of new fossil fuel developments must be front and centre of any decision on shale gas, not a secondary concern."

But the government's chief energy scientist, David MacKay, has warned that the UK would need to increase its nuclear fleet four-fold or its wind energy 20-fold to decarbonise heavy industry.

Both these options appear improbable, so the government is most likely to continue to give gas a prominent role in its energy strategy.

Ken Cronin, chief executive of the UK Onshore Operators Group, said: "The industry is pleased that the Committee supports our view that community engagement is key to public acceptance of shale gas exploration and that communities should share in the benefits of development."

Follow Roger on Twitter @rharrabin

Source: http://www.bbc.co.uk/news/science-environment-22300050#sa-ns_mchannel=rss&ns_source=PublicRSS20-sa

Outback Bowl washington redskins Carly Rae Jepsen Rose Bowl 2013 kim kardashian anderson cooper adrian peterson

Anger on streets as Bangladesh building toll passes 300

By Ruma Paul and Serajul Quadir

DHAKA (Reuters) - Bangladesh textile workers vented their anger on Friday, burning cars and clashing with police, as the death toll passed 300 following the collapse of a building housing factories that made low-cost garments for Western brands.

Miraculously rescuers were still pulling people alive from the rubble - 72 since daybreak following 41 found in the same room overnight - two days after the eight-storey building collapsed on the outskirts of the capital, Dhaka.

But there were fears that hundreds of people were still trapped in the wreckage of the building, which officials said had been built illegally without the correct building permits.

"Some people are still alive under the rubble and we are hoping to rescue them," said deputy fire services director Mizanur Rahman.

A spokesman for Prime Minister Sheikh Hasina said she had ordered the arrest of the owners of the building and of the five factories that occupied it.

Army spokesman Shahinur Islam said the death toll had reached 304 and H. T. Imam, an adviser to the prime minister, said it could exceed 350.

Anger over the working conditions of Bangladesh's 3.6 million garment workers, the overwhelming majority of them women, has grown steadily since the disaster, with thousands taking to the streets to protest on Friday.

About 2,350 people have been rescued, at least half of them injured, from the remains of the building in the commercial suburb of Savar, about 30 km (20 miles) from Dhaka.

An industry official has said 3,122 people, most of them female garment workers, had been in the Rana Plaza building despite warnings that it was structurally unsafe.

WRONG PERMIT, ILLEGAL FLOORS

Emdadul Islam, chief engineer of state run Capital Development Authority (CDA), said that the owner of the building had not received the proper building consent, obtaining a permit for a five-storey building from the local municipality, which did not have the authority to grant it.

"Only CDA can give such approval," he said. "We are trying to get the original design from the municipality, but since the concerned official is in hiding we cannot get it readily."

Furthermore, another three storeys had been added illegally, he said. "Savar is not an industrial zone, and for that no factory can be housed in Rana Plaza," Islam told Reuters.

Bangladesh is the second-largest exporter of garments in the world but many factories remained closed for a second day on Friday, with garment workers protesting against poor conditions and demanding the owners of the building and the factories it housed face harsh punishment.

Police and witnesses said protesters set fire to a number of vehicles and damaged other garment factories.

Dhaka District police chief Habibur Rahman identified the owner of the Rana Plaza building as Mohammed Sohel Rana, a leader of the ruling Awami League's youth front.

Imam, the prime minister's adviser, said Rana had "vanished into thin air".

"People are asking for his head, which is quite natural. This time we are not going to spare anybody," Imam said.

STRING OF FATAL INCIDENTS

Wednesday's collapse was the third major industrial incident in five months in Bangladesh. In November, a fire at the Tazreen Fashion factory on the outskirts of Dhaka killed 112 people.

"This incident is devastating for us as we haven't recovered from the shock of Tazreen fire yet," said Finance Minister Abul Maal Abdul Muhith, who visited the site on Friday.

Such incidents have raised serious questions about worker safety and low wages in Bangladesh and could taint the poor South Asian country's reputation as a producer of low-cost products and services.

North American and European chains, including British retailer Primark and Canada's Loblaw, said they were supplied by factories in the Rana Plaza building.

Mohammad Atiqul Islam, president of the Bangladesh Garment Manufacturers and Exporters Association (BGMEA), said the proprietors of the five factories inside the building had ignored the association's warning not to open on Wednesday after cracks had been seen in the building the day before.

"We asked not to open the factories and told them we will send our engineer, and until you get the green signal don't open the factories," Islam told Reuters.

"But, unfortunately, they violated our instructions," he said. A bank in the building did close on Wednesday after the warning.

PRAYERS, MOURNING

Savar residents and rescuers dropped bottled water and food on Thursday night to people who called out from between floors. Nearby, relatives identified their dead among dozens of corpses wrapped in cloth on the veranda of a school.

Special prayers were offered for the dead, injured and missing at mosques, temples and pagodas across Bangladesh on Friday.

Ten labor groups called for a strike on Sunday by workers at garment factories across the country.

Sixty percent of Bangladesh's garment exports go to Europe. The United States takes 23 percent and Canada takes 5 percent.

Primark and Loblaw, as well as PWT, a Danish company whose Texman brand clothes were also made in factories at Rana Plaza, operate under codes of conduct aimed at ensuring products are made in good working conditions.

The largest factory, New Wave Style, which listed many European and North American retailers as its customers, occupied the sixth and seventh floors, documents seen by Reuters showed.

(Additional reporting by Anis Ahmed in Dhaka, John Chalmers in New Delhi, Jessica Wohl and Nivedita Bhattacharjee in Chicago, Solarina Ho in Toronto, Robert Hertz in Madrid and Mette Kronholm Fraende in Copenhagen; Writing by Paul Tait; Editing by Alex Richardson)

Source: http://news.yahoo.com/dozens-rescued-hundreds-missing-bangladesh-toll-tops-270-055126500--sector.html

komen chrome for android hatchet leah messer freedom riders 9th circuit court of appeals gisele bundchen tom brady

Friday, April 19, 2013

The World's Largest Message-in-a-Bottle Brings Tidings of Soda

The world's largest message-in-a-bottle has taken to the seas, but it's not a call for rescue or some kind of timeless secret. Its message is just "drink our soda" but damned if it isn't still kind of cool. More »
    


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/ORpWGkR7snM/the-worlds-largest-message+in+a+bottle-brings-tidings-of-soda

michael buble Jenni Rivera Alive Facebook Down bo jackson bo jackson hanukkah justin tv

Apple Shares Dip Below $400, Representing A 16-Month Low

apple1Apple shares (NASDAQ:AAPL) are currently trading down at $398.11, 6.6 percent below yesterday's closing price of $426.24. It represents a stark downturn for the stock as well as a 16-month low. Earnings could be to blame as they are coming soon and investors are not sure what to expect.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/-FcCamFn9Vo/

the parent trap invisible children kony 2012 space weather sunspots pac 12 tournament sun storm tri

Dust Storm in China and Mongolia

On April 17, 2013, a dust storm blew through parts of China and Mongolia. The Moderate Resolution Imaging Spectroradiometer (MODIS) on NASA?s Aqua satellite captured this natural-color image the same day.

Although not as rich in sand as the Sahara Desert or the Empty Quarter of the Arabian Peninsula, this region still counts among the most dust-prone parts of the world. The April 17 dust storm blew through the Gobi Desert and the Badain Jaran Desert, which is home to some of our planet?s most complex sand dunes. To the west (not visible in this image) is the Taklimakan Desert, a sandy, salt-rich desert that can also produce substantial dust storms. The dust in this image may have included fine particles from multiple deserts, picking up additional material is it moved.

Northern Hemisphere springtime brings the greatest frequency of dust storms to the Gobi Desert. Dust storms are most common in March and April.

  1. References

  2. University Corporation for Atmospheric Research Forecasting Dust Storms. (Registration required).

NASA image courtesy Jeff Schmaltz, LANCE MODIS Rapid Response. Caption by Michon Scott.

Instrument:?
Aqua - MODIS

Source: http://earthobservatory.nasa.gov/NaturalHazards/view.php?id=80940&src=nhrss

i will always love you whitney houston 2012 grammy awards powerball results pebble beach golf beverly hilton roland martin whitney houston dead at 48

Wednesday, April 10, 2013

Transparent brain using hydrogel process

Apr. 10, 2013 ? Combining neuroscience and chemical engineering, researchers at Stanford University have developed a process that renders a mouse brain transparent. The postmortem brain remains whole -- not sliced or sectioned in any way -- with its three-dimensional complexity of fine wiring and molecular structures completely intact and able to be measured and probed at will with visible light and chemicals.

The process, called CLARITY, ushers in an entirely new era of whole-organ imaging that stands to fundamentally change our scientific understanding of the most-important-but-least-understood of organs, the brain, and potentially other organs, as well.

The process is described in a paper to be published online April 10 in Nature by bioengineer and psychiatrist Karl Deisseroth, MD, PhD, leading a multidisciplinary team, including postdoctoral scholar Kwanghun Chung, PhD.

"Studying intact systems with this sort of molecular resolution and global scope -- to be able to see the fine detail and the big picture at the same time -- has been a major unmet goal in biology, and a goal that CLARITY begins to address," Deisseroth said.

"This feat of chemical engineering promises to transform the way we study the brain's anatomy and how disease changes it," said Thomas Insel, MD, director of the National Institute of Mental Health. "No longer will the in-depth study of our most important three-dimensional organ be constrained by two-dimensional methods."

The research in this study was performed primarily on a mouse brain, but the researchers have used CLARITY on zebrafish and on preserved human brain samples with similar results, establishing a path for future studies of human samples and other organisms.

"CLARITY promises to revolutionize our understanding of how local and global changes in brain structure and activity translate into behavior," said Paul Frankland, PhD, a senior scientist in neurosciences and mental health at the Hospital for Sick Children Research Institute in Toronto, who was not involved in the research. Frankland's colleague, senior scientist Sheena Josselyn, PhD, added that the process could turn the brain from "a mysterious black box" into something essentially transparent.

An inscrutable place

The mound of convoluted grey matter and wiring that is the brain is a complex and inscrutable place. Neuroscientists have struggled to fully understand its circuitry in their quest to comprehend how the brain works, and why, sometimes, it doesn't.

CLARITY is the result of a research effort in Deisseroth's lab to extract the opaque elements -- in particular the lipids -- from a brain and yet keep the important features fully intact. Lipids are fatty molecules found throughout the brain and body. In the brain, especially, they help form cell membranes and give the brain much of its structure. Lipids pose a double challenge for biological study, however, because they make the brain largely impermeable both to chemicals and to light.

Neuroscientists would have liked to extract the lipids to reveal the brain's fine structure without slicing or sectioning, but for one major hitch: removing these structurally important molecules causes the remaining tissue to fall apart.

Prior investigations have focused instead on automating the slicing/sectioning approach, or in treating the brain with organic molecules that facilitate the penetration of light only, but not macromolecular probes. With CLARITY, Deisseroth's team has taken a fundamentally different approach.

"We drew upon chemical engineering to transform biological tissue into a new state that is intact but optically transparent and permeable to macromolecules," said Chung, the paper's first author.

This new form is created by replacing the brain's lipids with a hydrogel. The hydrogel is built from within the brain itself in a process conceptually similar to petrification, using what is initially a watery suspension of short, individual molecules known as hydrogel monomers. The intact, postmortem brain is immersed in the hydrogel solution and the monomers infuse the tissue. Then, when "thermally triggered," or heated slightly to about body temperature, the monomers begin to congeal into long molecular chains known as polymers, forming a mesh throughout the brain. This mesh holds everything together, but, importantly, it does not bind to the lipids.

With the tissue shored up in this way, the team is able to vigorously and rapidly extract lipids through a process called electrophoresis. What remains is a 3-D, transparent brain with all of its important structures -- neurons, axons, dendrites, synapses, proteins, nucleic acids and so forth -- intact and in place.

Going things one better

CLARITY then goes one better. In preserving the full continuity of neuronal structures, CLARITY not only allows tracing of individual neural connections over long distances through the brain, but also provides a way to gather rich, molecular information describing a cell's function is that is not possible with other methods.

"We thought that if we could remove the lipids nondestructively, we might be able to get both light and macromolecules to penetrate deep into tissue, allowing not only 3-D imaging, but also 3-D molecular analysis of the intact brain," said Deisseroth, who holds the D.H. Chen Professorship.

Using fluorescent antibodies that are known to seek out and attach themselves only to specific proteins, Deisseroth's team showed that it can target specific structures within the CLARITY-modified -- or "clarified" -- mouse brain and make those structures and only those structures light up under illumination. The researchers can trace neural circuits through the entire brain or explore deeply into the nuances of local circuit wiring. They can see the relationships between cells and investigate subcellular structures. They can even look at chemical relationships of protein complexes, nucleic acids and neurotransmitters.

"Being able to determine the molecular structure of various cells and their contacts through antibody staining is a core capability of CLARITY, separate from the optical transparency, which enables us to visualize relationships among brain components in fundamentally new ways," said Deisseroth, who is one of 15 experts on the "dream team" that will map out goals for the $100 million brain research initiative announced April 2 by President Obama.

And in yet another significant capability from a research standpoint, researchers are now able to destain the clarified brain, flushing out the fluorescent antibodies and repeating the staining process anew using different antibodies to explore different molecular targets in the same brain. This staining/destaining process can be repeated multiple times, the authors showed, and the different data sets aligned with one another.

Opening the door

CLARITY has accordingly made it possible to perform highly detailed, fine-structural analysis on intact brains -- even human tissues that have been preserved for many years, the team showed. Transforming human brains into transparent-but-stable specimens with accessible wiring and molecular detail may yield improved understanding of the structural underpinnings of brain function and disease.

Beyond the immediate and apparent benefit to neuroscience, Deisseroth cautioned that CLARITY has leapfrogged our ability to deal with the data. "Turning massive amounts of data into useful insight poses immense computational challenges that will have to be addressed. We will have to develop improved computational approaches to image segmentation, 3-D image registration, automated tracing and image acquisition," he said.

Indeed, such pressures will increase as CLARITY could begin to support a deeper understanding of large-scale intact biological systems and organs, perhaps even entire organisms.

"Of particular interest for future study are intrasystem relationships, not only in the mammalian brain but also in other tissues or diseases for which full understanding is only possible when thorough analysis of single, intact systems can be conducted," Deisseroth said. "CLARITY may be applicable to any biological system, and it will be interesting to see how other branches of biology may put it to use."

Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:


Story Source:

The above story is reprinted from materials provided by Stanford University Medical Center. The original article was written by Andrew Myers.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Kwanghun Chung, Jenelle Wallace, Sung-Yon Kim, Sandhiya Kalyanasundaram, Aaron S. Andalman, Thomas J. Davidson, Julie J. Mirzabekov, Kelly A. Zalocusky, Joanna Mattis, Aleksandra K. Denisin, Sally Pak, Hannah Bernstein, Charu Ramakrishnan, Logan Grosenick, Viviana Gradinaru, Karl Deisseroth. Structural and molecular interrogation of intact biological systems. Nature, 2013; DOI: 10.1038/nature12107

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_environment/~3/aprD_TDWLH8/130410131223.htm

walmart black friday walmart black friday Target Black Friday PacSun apple store bestbuy bestbuy

Non-standard spacing in between floor joists? - DIY Home ...






SBay: Sorry I wasn't more clear. If you change from 16" on center you will waist plywood as the end will not land on framing and would have to be cut. If you are heating or cooling insulating the floor is a good idea. You do want air below the insulation so some kind of wire mesh should be facing the ground to keep critters out of the insulation. What we do we a shed like yours is place the timbers in the ground where you need them straight and level, they will absorb moisture so you want a 6 mil poly to protect the rest of the framing from moisture Then we build the floor beside it, make sure it's square and attach wire mesh and then flip it over on top of the timbers. Attach it to 1 beam with treated nails or screws ( the treatment in the wood eats reguler nails and screws).
Check your frame for square and then attach to the other beam, now your ready for insulation. ( Measure on angle from corner to corner and compare to oposite corners, adjust until both measure the same)
Keep in mind that lumber is not cut to length except for studs so all framing bits and peices have to be cut to length ) a 12ft 2x6 will be 1/4 to 3/4" to long.
Dropping 3/4" is just a term used to make sure plywood fits the layout. So when you lay out the endframing members for floors and walls, put the two peices together and hook your tape to one end and mark it at 15 1/4, 31 1/4 , 47 1/4 and so on, this will make the 96" plywood land half way on the joist or stud.
For floor plywood, houses are built with 5/8 tongue and grove, 5/8 should be enough for your floor and tongue and groove is a must. There will be tips for that too.


Last edited by nealtw; Yesterday at 07:11 PM.

Source: http://www.houserepairtalk.com/f32/non-standard-spacing-between-floor-joists-15825/

mega ball winning numbers baltimore county current tv megamillions ncaa basketball tournament 2012 megamillions winning numbers lotto winner

Syria: Suicide car bombing kills 15 in Damascus

This photo released by the Syrian official news agency SANA, shows smoke rising from burned cars after a huge explosion shook the Sabaa Bahrat Square, one of the capital's biggest roundabouts, in Damascus, Syria, Monday, April. 8, 2013. A car bomb rocked a busy residential and commercial district in central Damascus on Monday, killing more than a dozen with many more injured and sending a huge cloud of black smoke billowing over the capital?s skyline, Syrian state-run media said. (AP Photo/SANA)

This photo released by the Syrian official news agency SANA, shows smoke rising from burned cars after a huge explosion shook the Sabaa Bahrat Square, one of the capital's biggest roundabouts, in Damascus, Syria, Monday, April. 8, 2013. A car bomb rocked a busy residential and commercial district in central Damascus on Monday, killing more than a dozen with many more injured and sending a huge cloud of black smoke billowing over the capital?s skyline, Syrian state-run media said. (AP Photo/SANA)

This photo released by the Syrian official news agency SANA, shows a Syrian fire fighter extinguishing a burning car after a huge explosion shook the Sabaa Bahrat Square, one of the capital's biggest roundabouts, in Damascus, Syria, Monday, April. 8, 2013. A car bomb rocked a busy residential and commercial district in central Damascus, killing at least a dozen people with more than fifty injured and causing heavy material damage, a Syrian government official said. (AP Photo/SANA)

This photo released by the Syrian official news agency SANA, shows Syrian fire fighters extinguishing burning cars after huge explosion shook the Sabaa Bahrat Square, one of the capital's biggest roundabouts, in Damascus, Syria, Monday, April. 8, 2013. A car bomb rocked a busy residential and commercial district in central Damascus, killing at least a dozen people with tens more injured and causing heavy material damage, a Syrian government official said. (AP Photo/SANA)

This photo released by the Syrian official news agency SANA, shows Syrians inspecting a damaged car at the scene of a car bomb attack near the Sabaa Bahrat Square, one of the capital's biggest roundabouts, in Damascus, Syria, Monday, April. 8, 2013. A car bomb rocked a busy residential and commercial district in central Damascus, killing at least a dozen people with tens more injured and causing heavy material damage, a Syrian government official said. (AP Photo/SANA)

This photo released by the Syrian official news agency SANA, shows smoke rising from burned cars after a huge explosion shook the Sabaa Bahrat Square, one of the capital's biggest roundabouts, in Damascus, Syria, Monday, April. 8, 2013. A car bomb rocked a busy residential and commercial district in central Damascus on Monday, killing more than a dozen with many more injured and sending a huge cloud of black smoke billowing over the capital?s skyline, Syrian state-run media said. (AP Photo/SANA)

(AP) ? A suicide bomber detonated a car packed with explosives on Monday in a busy residential and financial district of central Damascus, killing at least 15 people, setting cars and buildings on fire and sending plumes of black smoke rising the capital, Syrian state-run media said.

The explosion came as U.N. chief Ban Ki-moon said inspectors were ready to deploy to Syria within 24 hours to investigate reports of chemical weapon attacks, but have not yet received permission from President Bashar Assad's government.

The blast, described by state-run Syrian TV as a terrorist suicide bombing, occurred near Sabaa Bahrat Square, one of the capital's biggest roundabouts. The Syrian central bank, the Finance Ministry and state-run investment agency, a mosque and a school are located nearby.

The explosion also wounded 146 people, according to the official news agency SANA.

It was the latest in a series of car bombs and suicide bombings to hit the Syrian capital in recent months. The two-year civil war, which the U.N. says has killed more than 70,000 people, has become increasingly chaotic as rebels press closer to Assad's seat of power in Damascus after seizing large areas in northern and eastern parts of the country.

TV images showed thick black smoke billowing from a wide street with several cars on fire. At least six bodies were seen lying on the pavement. Paramedics carried a young woman lying on a stretcher, her face bloodied, into an ambulance.

Shaken teenage students holding their backpacks were seen walking away. The blast occurred some 20 meters (yards) from the Bukhari School.

Among the buildings damaged was the state-run Syrian Investment Agency. Several cars in the building's parking lot were set ablaze in the explosion. Witnesses said a suicide attacker tried to storm the building with his vehicle but was stopped by guards. He then detonated his explosives outside the building.

In the early days of the uprising, the Sabaa Bahrat Square was home to huge pro-regime demonstrations that took place with a giant poster of Assad hanging as a backdrop over the central bank building.

"I was in the square when I heard a strong explosion that threw me on the ground," civil servant Hussein Khalil, 32, told The Associated Press at the scene. "I ran and saw what happened."

Electrician Mohammed Ali Kheir, 21, said he was nearby and felt the pressure of the blast. "I immediately ran here and helped paramedics evacuate four wounded people," he said.

"Is this the freedom that Qatar and Saudi Arabia want?" asked the man, referring to the Gulf Arab countries that have backed Syrian rebels fighting to remove Assad from power.

In Syrian TV footage, one woman shouted sarcastically: "Thank you, Hamad!" She was referring to the emir of Qatar, a major rebel supporter. "Is this what you want?" she asked.

Assad's regime denies there is a popular uprising and refers to the rebels as "terrorists" and "mercenaries," allegedly backed by foreign powers trying to destabilize the country.

Prime Minister Wael al-Halqi, visiting the scene, said the blast targeted the Syrian economy.

"This is the work of cowards," he said, vowing that the army would continue to crush all armed groups.

According to the TV footage, the dead included a young man whose face was blown off by the force of the blast. Shortly after, another man is seen covering the victim's head with his T-shirt.

Nearby, several men are seen twisting the wreckage of a car, trying to rescue a man who appears motionless in the back seat of a car.

Fire fighters struggled to extinguish flames that engulfed the two buildings near the site of the explosion as well as a row of cars near the roundabout.

The last large explosion in central Damascus was on March 21, when a suicide bomb ripped through a mosque in the heart of the capital. That bombing killed 42 people, including a top Sunni Muslim preacher and outspoken supporter of Assad in what was one of the most brazen assassinations of the war.

A month earlier, a suicide car bombing near the ruling Baath Party headquarters, just a few blocks from Monday's site, killed 53 people and wounded more than 200, according to state media.

Anti-regime activists at the time put the death toll at 61, which would make it the deadliest bombing in the capital in the two-year Syrian civil war.

There was no claim of responsibility for those two Damascus attacks and there was no immediate claim for Monday's blast.

In the past, Jabhat al-Nusra, an Islamic militant group with ties to al-Qaida that the U.S. has designated as a terrorist organization, has claimed responsibility for some of the deadliest suicide bombings targeting regime and military facilities across the country.

The violence has shattered the sense of normalcy that the Syrian regime has desperately tried to maintain in Damascus, a city that was until recently mostly insulated from the bloodshed and destruction that has left other urban centers in ruins.

The anti-Assad rebels launched an offensive on Damascus in July after a stunning bombing on a high-level government crisis meeting that killed four top regime officials, including Assad's brother-in-law and the defense minister. Following that attack, rebel groups that had established footholds in the suburbs pushed in, battling government forces for more than a week before being routed and swept out.

Since then, government warplanes have pounded opposition strongholds on the outskirts of the capital, and rebels have managed only small incursions on the city's southern and eastern sides. More recently, they have taken to firing deadly mortar shells deep into the capital as way to loosen the regime's grip on power.

Assad's government has asked the U.N. chief to investigate an alleged chemical weapons attack by rebels on March 19 on a village in northern Syria. Both the rebels and the regime traded blame for the alleged attack in the village of Khan al-Assal in the northern Aleppo province, which has not been confirmed.

Also Monday, a Syrian human rights group said nearly 9,000 Syrian government troops have been killed since the uprising started in March 2011. The Syria-based Violations Documentation Center, which tracks the dead, wounded and missing, said 8,785 Syrian troops have died in the fighting.

It said the rare report on the regime's death toll was compiled from government and opposition sources.

At the start of the revolt, authorities published names of the fallen troops daily. As the uprising turned more violent and eventually became a civil war, reports of casualties on the government side vanished from the public domain.

___

AP writers Barbara Surk and Bassem Mroue in Beirut and Mike Corder in The Hague contributed.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-04-08-ML-Syria/id-7cedde0da0d9464496e9aaa6f33b46d3

penguins the band colton dixon houston weather dwyane wade the night they drove old dixie down levon